Phospho stat5
WebA Life Sciences and Diagnostics business focused on enabling scientists and healthcare professionals to advance research, discovery and detection to improve global health … WebSee all STAT5 primary antibodies Description Rabbit monoclonal [E208] to STAT5 (phospho Y694) Host species Rabbit Tested applications Suitable for: WB, IHC-P, ELISA more …
Phospho stat5
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WebSTAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine signaling. STAT5 consists of two closely related family members, STAT5A and STAT5B, which exhibit 96% sequence homology and are functionally redundant. Upon activation, STAT WebPhospho-STAT5 pTyr694 Antibody (ST5P-4A9) Product Data Sheet Product Specific Information General Information For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and …
WebCell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr 701), phospho-STAT3 (pTyr 705), and phospho-STAT5 (pTyr 694) in cultured cell lines 检测培养细胞系中磷酸化-STAT1（pTyr(pTyr 701 ),磷酸化-STAT3 (pTyr 705 ), 和磷酸化-STAT5 (pTyr 694 )的基于细胞的ELISA试剂盒 WebSTAT5 alpha is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes, the proteins are 90% identical at the amino acid level. STAT5 proteins are involved in cytosolic signalling and in mediating the expression of specific genes. Aberrant STAT5 activity has been shown to be closely connected to a wide rang… Webcomparable activation of STAT3 and STAT5. In Tyr845Phe, Tyr892Phe and Tyr922Phe mutants of mFLT3Asp838Val,theexpressionofPim-2wassignificantly reduced compared to that of mFLT3Asp838Val or ...
WebSTAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine signaling. STAT5 consists of two closely related family members, STAT5A and STAT5B, which exhibit 96% sequence homology and are functionally redundant. Upon activation, STAT5 is phosphorylated by receptor tyrosine ...
WebMar 21, 2024 · The expression of STAT5 was thus the only noted difference in signaling proteins between HMC-1.2 and HMC-1.3 cells. However, the ratio of phospho-STAT5 to total STAT5 was similar in both cell lines with D816V (alone or in combination with V560G) (Figure 2C). Cells with gain-of function in KIT are known to appear refractory to SCF . chipmunk at the gas pumpWebDec 18, 2024 · Assessing IL-2-induced phosopho-STAT5 (pSTAT5) content can reveal the cytokine responsiveness of individual T cells. Identifying distinct T cell subsets by nuclear transcription factors, such as Foxp3, and concurrently quantifying intracellular pSTAT5, however, has been technically challenging. chipmunk artistWebTHUNDER™ Phospho-STAT5 (Y694/Y699) TR-FRET Cell Signaling Assay Kit. Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-STAT5 (Y694) in cell lysates. Full assay validation can be found in the Technical Data Sheet. Detailed assay protocols are described in the Generic User Manual. KIT-STAT5P-100. Size. grants for photographers 2023WebJun 20, 2013 · GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia Granulocyte-macrophage-colony-stimulating factor (GM-CSF) hypersensitivity is a hallmark of juvenile myelomonocytic leukemia (JMML) but has not been systematically shown in the related human disease chronic myelomonocytic … grants for photography businessWebPhospho-Stat5 (Tyr694) Antibody detects endogenous levels of Stat5a only when phosphorylated at Tyr694 and Stat5b when phosphorylated at Tyr699. The antibody does … grants for photography equipment for kidsWebSTAT5 is a transcription regulator and is involved in cell differentiation, proliferation, and survival, in response to several cytokines, such as interleukins, erythropoietin, growth … chipmunk baby clothesWebMay 31, 2024 · p-Stat5a/b Antibody (5G4) is an IgG 1 mouse monoclonal p-Stat5a/b antibody suitable for the detection of Tyr 694 phosphorylated Stat5a and Tyr 699 phosphorylated Stat5b of mouse, rat and human origin by WB, IP and IF. p-Stat5a/b Antibody (5G4) is available as the non-conjugated anti-p-Stat5a/b antibody form. Stat5 (Signal … chipmunk at computer