Lecithin-cholesterol acyltransferase-like
Nettet15. des. 2000 · Lecithin cholesterol acyltransferase was identified as a unique plasma enzyme in 1962 by Glomset [3]. Subsequent work revealed that human LCAT is a glycoprotein with a polypeptide mass of 49 kDa, augmented to around 60 kDa by a 20% carbohydrate mass. Its secondary structure contains β-sheet and α-helical elements, … Nettet26. mai 2000 · A Candidate Diacylglycerol Acyltransferase with Identity to Human LCAT. Because abundant TG synthesis remained in the absence of the four yeast DGAT-like …
Lecithin-cholesterol acyltransferase-like
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Nettet16. mar. 2006 · Objectives— Lecithin:cholesterol acyltransferase deficiency (LCAT-def) is characterized by low levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) and the accumulation of lipoprotein-X (LpX). Despite the low HDL, atherosclerosis is uncommon in LCAT-def. The decreased LDL would be a possible explanation but the … NettetThe free cholesterol in the HDL2 particles is esterified by LCAT (Lecithin:cholesterol acyltransferase), generating mature HDL particles [693], from which the cholesteryl esters are removed into ...
NettetAcetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group. Examples include: Histone acetyltransferases including CBP histone acetyltransferase. Choline acetyltransferase. Chloramphenicol acetyltransferase. Serotonin N-acetyltransferase. NatA Acetyltransferase. NatB acetyltransferase. Nettet1. des. 1994 · Results show LCAT to be a significantly better indicator of the risk of coronary artery disease than either total cholesterol or triglycerides. This study grew out of observations of certain lecithin:cholesterol acyltransferase (LCAT) abnormalities in patients with atherosclerosis. We studied the interrelationships among LCAT, and total …
Nettet30. okt. 2024 · Background: although high-density lipoprotein has cardioprotective effects, the association between serum high-density lipoprotein cholesterol (HDL-C) and hypertension is poorly understood. Therefore, we investigated whether high and low concentrations of HDL-C are associated with high blood pressure (HBP) using a large … Nettet12. apr. 2024 · Background: Menopause is a time when women experience a number of physiological and anatomical changes resulting from a decline in ovarian function. It can be concluded that cardiovascular disease increases in perimenopausal and postmenopausal women, irrespective of age-related changes. Engaging in the amount of moderate …
NettetThe plasma 1ecithin:cholesterol acyltransferase reaction JOHN A. GLOMSET Department of Medicine and Regional Primate Research Center, University of Washington, Seattle, Washington 98105 ABSTRACT Evidence for the existence of a plasma lecithin : cholesterol acyltransferase is reviewed with emphasis not only on the lipid reactants, …
NettetLecithin cholesterol acyltransferase deficiency is a disorder of lipoprotein metabolism. The disease has two forms: Familial LCAT deficiency, in which there is complete LCAT … inconsistency\\u0027s uhNettetThe function of lecithin:cholesterol acyltransferase (LCAT) The function of lecithin:cholesterol acyltransferase (LCAT) Scand J Clin Lab Invest. 2024 … inconsistency\\u0027s uyNettet1. jun. 2000 · Analysis of LCAT transgenic animals has established the importance of evaluating HDL function, as well as HDL plasma levels, to predict atherogenic risk. In the past several years significant advances have been made in our understanding of lecithin-cholesterol acyltransferase (LCAT) function. LCAT beneficially alters the plasma … inconsistency\\u0027s up