WebThis is an open-label study of INCB047986 given to two distinct groups of patients (Group 1 and Group 2) with advanced malignancies. The purpose of the .. WebOct 24, 2024 · Drug Profile INCB 47986 Alternative Names: INCB-47986; INCB047986 Latest Information Update: 24 Oct 2024 Price : $50 * Buy Profile Adis is an information provider. …
NCT01929941 DrugSheet
WebThis is an open-label study of INCB047986 given to two distinct groups of patients (Group 1 and Group 2) with advanced malignancies. The purpose of the study is to evaluate the safety, tolerability and pharmacokinetics of INCB047986 and to determine the maximum tolerated dose of INCB047986 in combination with gemcitabine and nab paclitaxel in a … WebMay 28, 2014 · INCB047986 placebo will be orally self-administered once daily (QD) for 28 days. Clinical Trial Outcome Measures Primary Measures. Percentage of participants with adverse events, changes in electrocardiograms (ECGs), vital signs, physical examinations, or clinical laboratory evaluations. portland kitchen supply store
An Open-Label Study of a Novel JAK-inhibitor, INCB047986, Given …
WebAn orally bioavailable inhibitor of Janus-associated kinases (JAK), with potential antineoplastic activity. Upon oral administration, INCB047986 specifically binds to and inhibits the phosphorylation of JAK, which affects JAK-dependent signaling and may lead to an inhibition of cellular proliferation in JAK-overexpressing tumor cells. The JAK-STAT … WebEnsaios clínicos em tumore solido avanzato con evidenza di linea germinale o brca somatica. Registro de ensaios clínicos. ICH GCP. WebINCB047986 in Rheumatoid Arthritis A Double-Blind, Placebo-Controlled Study Exploring the Safety, Tolerability, and Efficacy of a 28-Day Course of INCB047986 in Subjects With Active Rheumatoid Arthritis optics compatibility matrix cisco.com