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Eif4a2

WebTarget Information. eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a … WebTarget Information eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre …

eIF4A2 drives repression of translation at initiation by …

WebJul 21, 2024 · Subtypes eIF4A1 and eIF4A2 are required for translation initiation, but eIF4A3 participates in the exon junction complex (EJC) and functions in RNA metabolism including nonsense-mediated RNA decay (NMD). No small molecules for NMD inhibition via selective inhibition of eIF4A3 have been discovered. WebIL17猪白介素17ELISA试剂盒公司正在销售的产品：矢车菊苷γ2ELISA检测试剂盒 CENTγ2Human Cen... mbcra and t\\u0026e https://gftcourses.com

RNA-Based next generation sequencing complements but

WebA — HUMAN NECESSITIES; A61 — MEDICAL OR VETERINARY SCIENCE; HYGIENE; A61K — PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES; A61K47/00 — Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active … Webof eIF4A2 (15), can rescue the eIF4A2 KD effects on ESC proliferation, morphology, and the expression of differentiation and 2C transcripts (Fig. 1E, and fig. S1, P and Q). These results established the essential role of eIF4A2 in maintaining the pluripotency. However, over expression of eIF4A2 in ESCs (fig. S2A) had minimal effects on the WebFeb 7, 2024 · The most prominent examples are those of SNORA63/EIF4A2, SNORA63E/LINC00888, SNORD66/EIF4G1. These couples undergo CNA in a significant portion of patients in HNSC, KIRC, SKCM, OV, and GBM; in all these tumor types, these 3 couples are altered in similar percentages of patients, ranging from 7–8% in OV cancer, … mbc planning portal log in

EIF4A2 interacts with the membrane protein of …

Category:Anti-EIF4A2 Rabbit Polyclonal Antibody VWR

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Eif4a2

EIF4A2 interacts with the membrane protein of …

Web13682 Ensembl ENSG00000156976 ENSMUSG00000022884 UniProt Q14240 P10630 RefSeq (mRNA) NM_001967 NM_001123037 NM_001123038 NM_013506 … WebPredominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (PubMed:16357133). Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma. Interacts (via MI domains) with EIF4A2 (By similarity). Interacts (via MI domains) with ...

Eif4a2

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WebApr 1, 2024 · The EIF4A2 gene is located approximately 1 MB away from BCL6 on chromosome 3q27 in a tail-to-tail orientation ( Fig. 2 ), and this rearrangement is reportedly produced by a paracentric inversion which is cryptic to FISH analysis [39], as was also seen in the current report. WebJun 14, 2024 · Abstract. Eukaryotic initiation factor 4A (eIF4A), the enzymatic core of the eIF4F complex essential for translation initiation, plays a key role in the oncogenic …

WebJul 1, 2024 · EIF4A2 is a direct target of miR-5195-3p We used TargetScan and miRBase to analyze the underlying mechanism of miR-5195-3p in the PTX sensitivity of TNBC cells. Of the predicted target genes of miR-5195-3p, EIF4A2 was selected for … WebTarget Information eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre …

WebJul 1, 2000 · Isolation and mapping of the human EIF4A2 gene homologous to the murine protein synthesis initiation factor 4A-II gene Eif4a2. The DEAD box protein eIF4A. 2. A cycle of nucleotide and RNA-dependent conformational changes. Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII.

WebJun 1, 2024 · These results suggest that eIF4A2 is a host factor required for HIV-1 infection. The phenotype of the different shRNAs further suggests that the inhibition of NL4-3luc-RC infection may not be an off-target effect. 3.2. Depletion of eIF4A2 reduces the efficiency of HIV-1 cDNA synthesis.

WebRabbit polyclonal antibody to eIF4A2 (eukaryotic translation initiation factor 4A, isoform 2) Suggested starting dilutions are as follows: WB: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. Type: Primary Antigen: EIF4A2 Clonality: Polyclonal Clone: mbc play liveWebIn molecular biology, housekeeping genes are typically constitutive genes that are required for the maintenance of basic cellular function, and are expressed in all cells of an organism under normal and patho-physiological conditions. Although some housekeeping genes are expressed at relatively constant rates in most non-pathological situations, the expression … mbcr-100hdWebThe eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to … mbcp online