WebKey features and details Rabbit polyclonal to CISH/CIS - C-terminal Suitable for: IHC-P, WB Reacts with: Rat, Human Isotype: IgG You may also be interested in Protein Recombinant Human CISH/CIS protein (ab117057) Primary Anti-C6orf134/TAT antibody (ab184778) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) View more associated products … WebMar 28, 2024 · Cish, participates within a multi-molecular E3 ubiquitin ligase complex, which ubiquitinates target proteins. It has an inhibitory effect on T cell activation mediated by PLC-γ1 regulation, and ...
Internal checkpoint regulates T cell neoantigen reactivity and ...
WebAnti-CISH antibody produced in mouse. IgG fraction of antiserum, buffered aqueous solution. View Price and Availability. ... Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Immunogen. CISH (NP_659508.1, 1 a.a. ~ 258 a.a) full-length human protein. Sequence. Packaging. 100 μg. WebNov 1, 2014 · The founding member of the SOCS family, cytokine inducible SH2-containing protein (CISH), and the seven other members present in mammals, SOCS-1 to -7, share a common structure. All SOCS proteins contain a central SH2 domain with an N-terminal extended SH2 subdomain (ESS) and a C-terminal 40 amino acid (aa) motif, the SOCS box. important history events el salvador
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WebHome / Human / CISH Antibody. Western blot analysis of extracts of 293T cells, using CISH antibody (15-585) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. … WebOct 5, 2024 · One of the potential targets for cytokine-mediated activation of NK cells is the CIS protein. CIS is a SH 2 -containing cytokine-induced protein encoded by the CISH gene. CIS decreases the susceptibility of NK cells to IL-15 and thus is a powerful check point for inactivation of their cytotoxicity. WebFluorescence in situ hybridization (FISH) technologies enable rapid detection of chromosome aberrations in all manner of tissues, including both fresh and archival specimens. These technologies have gained broad acceptance in the clinical cytogenetic and research communities. important historic places left to rot